Chunlong Ma and Lawrence Pinto Published Manuscript in Journal of the American Chemical Society
In collaboration with Robert Lamb (Professor and Department Chair, Molecular Biosciences), Chunlong Ma (Past Postdoctoral Fellow) and Lawrence Pinto (Emeritus Professor) published manuscript in the Journal of the American Chemical Society. Flipping in the Pore: Discovery of Dual Inhibitors that Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel looks at the genetics of the flu and how the "flip-flop mode of drug binding correlates with the structure-activity relationship (SAR) and has paved the way for the next round of rational design of broad-spectrum antiviral drugs.”9 December 2014